Identifying the natural products in the treatment of atherosclerosis by increasing HDL-C level based on bioinformatics analysis, molecular docking, and in vitro experiment

Table 1 Molecular docking results of AS with target proteins

MOL	Targets	Pathway	Protein names	Uniprot ID	PDB ID	Affinity (kcal/mol)
Genistein	APOA1	Cholesterol metabolism	Apolipoprotein A-I	P02647	1GW3	− 5.1
Genistein	CETP	Cholesterol metabolism	Cholesteryl ester transfer protein	P11597	4F2A	− 7.7
Genistein	LIPC	Cholesterol metabolism	Hepatic triacylglycerol lipase	P11150	AlphaFold	− 9.5

ISSN: 1479-5876