Table 3 Evaluation of the diagnostic efficiency of single and combined tests for NSCLC [%]
Test item | SEN% | SPE% | PPV% | NPV% | AC% | LR +  |
|---|---|---|---|---|---|---|
Total CTCs | 67.3 | 83.9 | 86.8 | 61.9 | 73.8 | 4.2 |
LCTCs | 38.8 | 67.7 | 65.5 | 41.2 | 50.0 | 1.2 |
SCTCs | 65.3 | 93.5 | 94.1 | 63.0 | 76.3 | 10.1 |
Triploid CTCs | 57.1 | 96.8 | 96.6 | 58.8 | 72.5 | 17.7 |
Tetraploid CTCs | 51.0 | 87.1 | 86.2 | 52.9 | 65.0 | 4.0 |
Multiploid CTCs | 28.6 | 96.8 | 93.3 | 46.2 | 55.0 | 8.9 |
Total CTECs | 77.6 | 77.4 | 84.4 | 68.6 | 77.5 | 3.4 |
LCTECs | 67.3 | 67.7 | 76.7 | 56.8 | 67.5 | 2.1 |
SCTECs | 67.3 | 77.4 | 82.5 | 60.0 | 71.3 | 3.0 |
Triploid CTECs | 49.0 | 90.3 | 88.9 | 52.8 | 65.0 | 5.1 |
Tetraploid CTECs | 36.7 | 71.0 | 66.7 | 41.5 | 50.0 | 1.3 |
Multiploid CTECs | 59.2 | 74.2 | 78.4 | 53.5 | 65.0 | 2.3 |
SCC + CEA + CYFRA 21–1 | 52.2 | 75.8 | 77.4 | 50.0 | 61.3 | 2.17 |
CT/PET-CT diagnosis | 57.1 | 77.4 | 80.0 | 53.3 | 65.0 | 2.48 |