A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs

Table 2 Statistical parameters for ROC analysis of CTCs and CTECs for NSCLC

Test item	AUC	Cutoff value	Std. Error	P	95% CI
Total CTCs	0.815	11.5	0.047	< 0.0001	0.722–0.907
_LCTCs	0.663	6.5	0.061	0.015	0.544–0.782
_SCTCs	0.815	6.5	0.046	< 0.0001	0.724–0.906
Triploid CTCs	0.809	6.5	0.047	< 0.0001	0.717–0.901
Tetraploid CTCs	0.698	4.5	0.056	< 0.001	0.634–0.852
Multiploid CTCs	0.646	6.5	0.062	0.029	0.525–0.766
Total CTECs	0.739	10.5	0.062	< 0.001	0.618–0.860
_LCTECs	0.691	8.5	0.064	0.004	0.566–0.815
_SCTECs	0.781	2.5	0.053	< 0.0001	0.679–0.884
Triploid CTECs	0.716	3.5	0.058	0.001	0.602–0.830
Tetraploid CTECs	0.677	2.5	0.063	0.008	0.555–0.799
Multiploid CTECs	0.675	7.5	0.063	0.009	0.550–0.799
Total CTCs + CTECs	0.826	–	0.047	< 0.0001	0.734–0.917
_SCTCs + _SCTECs	0.898	–	0.036	< 0.0001	0.828–0.968
Triploid(CTCs + CTECs)	0.872	–	0.040	< 0.0001	0.794–0.950

Large CTCs, _LCTCs, small CTCs, _SCTCs, Large CTECs, _LCTECs, small CTECs, _SCTECs

ISSN: 1479-5876