Fig. 6

Characteristics of the mutant genes detected in circulating tumor DNA (ctDNA) and tumor DNA (tDNA). A Schematic figure illustrating the sources of ctDNA and tDNA. B The positive rates of ctDNA mutations among benign, adenocarcinoma (AC), and squamous cell carcinoma (SCC) subgroups of the enrolled 28 patients. C Venn figure showing the target genes covered in panels of both ctDNA and tDNA. D Heatmap detailing the mutant genes detected in the ctDNA and matched tDNA of the 9 patients with fractional abundance in the upper left corner as well as the microsatellite instability (MSI) status and tumor mutation burden (TMB) score; VUS: variant of uncertain significance