Fig. 3
From: Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell niche
Knockout of iNOS changed the proliferative status within intestinal crypts. A Representative images of immunohistochemical staining for Ki67, BrdU and pHH3 in the crypts of the mouse ileum. Tissues were collected from the control group and iNOS−/− group mice at 1.5 h after BrdU injection. Bar = 50 μm. B Quantification of cells positive for Ki67, BrdU, and pHH3 staining and statistical analysis between the control and iNOS−/− groups. ***P < 0.001, ****P < 0.0001, n = 5