Fig. 2From: Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell nicheiNOS deletion impaired the morphology of the intestine. A Gross images of gastrointestinal tract samples from the control and iNOS−/− groups. B The length of the small intestine (SI) of iNOS−/− group mice was significantly shorter than that of control group mice (n = 3). C There was no difference in the length of colons from the control and iNOS−/− groups (n = 3). D Representative images of hematoxylin and eosin staining in the ileum for the control group and iNOS−/− mice. Bar = 50 μm. E Statistical analysis of villus height, crypt depth, crypt width and crypt density between the control group and iNOS−/− group. n.s: P > 0.05, *P < 0.05, ****P < 0.0001, n = 3Back to article page