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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Silencing HOXC13 exerts anti-prostate cancer effects by inducing DNA damage and activating cGAS/STING/IRF3 pathway

Fig. 6

Effects of silencing HOXC13 on DNA damage-induced cGAS/STING/IRF3 pathway in 22RV1 cells. A Accumulation of dsDNA in cells. B Protein bands for nucleus and cytoplasm. C Expression statistics of HOXC13 and γH2AX proteins. D Protein bands for cytoplasm. E Expression statistics of cGAS, p-STING, STING, p-IRF3 and IRF3 proteins. (vs. siNC group: *P < 0.05, **P < 0.01, ***P < 0.001; vs. siHOXC13-3 group: ###P < 0.001; vs. siHOXC13-4 group: $$P < 0.01, $$$P < 0.001)

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Journal of Translational Medicine

ISSN: 1479-5876

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