Fig. 4

Overexpression of MAD2L2 enhances the proliferation, migration, and invasive capabilities of glioma cells. A, B, D CCK8, colony formation assay and EDU assay showed that overexpression of MAD2L2 significantly enhanced the proliferation ability of U118 and LN229 cells. C flow cytometry analysis showed that ectopic expression of MAD2L2 expedited G1/S phase progression E, F overexpression of MAD2L2 improved the migration and invasion ability of glioblastoma cell lines. *P < 0.05, **P < 0.01, ***P < 0.001