Fig. 5
LocusZoom plot for sTIE1 protein levels and IOP in TIE1 gene region. LocusZoom plot of genetic associations of variants within TIE1 gene region with circulating sTIE1 protein levels (A) and IOP (B). The purple diamond is the variant with the highest posterior probability of being the shared causal variant underlying the two traits (PPshared), as determined by coloc. Points are color-coded based on their LD (r2) relative to the variant with the highest PPshared. LocusZoom plot of sTIE1 genetic associations using a 100kB window is shown in Additional file 22: Figure S7