Fig. 7
From: Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils
IFN-α2 regulates the secretion of IL-8, CSF-3 and CCL20 by activating the p-STAT1 and p-STAT2 through IFNAR1 receptor. A The protein expression of IFNAR1 in control group and IFNAR1-KD group. B Fold change of CSF-3, IL-8, and CCL20 in the cell supernatant by ELISA. C Protein expression with or without adding IFN-α2 in control UC-MSCs and IFNAR1-KD UC-MSCs. D Fold change of CSF-3, IL-8, and CCL20 in the cell supernatant with or without adding Fludarabine by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001. KD knockdown