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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils

Fig. 5

Pretreated UC-MSCs with IFN-α2 enhanced neutrophils infiltration into liver. A Representative Giemsa staining of blood smears of rat in Anti-PMN group and Isotype group (Left) and number of neutrophils per field counted (Right). White arrows indicate stained neutrophils. Scale bars, 20 μm. n = 5. B Animal modeling and treating diagram. C MPO positive neutrophils of liver tissues by IHC in each group (Left) and MPO positive neutrophils count of each field (Right). Red arrows indicate stained neutrophils. Scale bars, 20 μm. D HE staining and Sirius Red staining of liver tissues (Left) and the positive area of Sirius Red staining statistics (Right). Scale bars, 50 μm. E Biochemical index (AST, ALT, ALB, TBil) in different groups. Number of each group ≥ 3. *P < 0.05, **P < 0.01, ***P < 0.001

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