Table 1 Demographic data and disease characteristics by age group
Patients | Children and adolescents (< 18 years) | Adults (≥ 18 years) | Total cohort |
|---|---|---|---|
n = 33 | n = 123 | N = 156 | |
Sex, n (%) | |||
Female | 16 (48.5%) | 50 (40.7%) | 66 (42.3%) |
Male | 17 (51.5%) | 73 (59.3%) | 90 (57.7%) |
Age, years | |||
Mean (SD) | 8.9 (4.9) | 52.5 (14.2) | 43.3 (22.0) |
Median (Q1, Q3) | 9.0 (6.0, 12.0) | 55.0 (45.0, 63.0) | 49.5 (22.5, 62.0) |
Min, max | 0, 17 | 19, 79 | 0, 79 |
ICH age group, n (%) | |||
Infants/toddlers (28 days to 23 months) | 2 (6.1%) | NA | 2 (1.3%) |
Children (2 to 11 years) | 18 (54.5%) | NA | 18 (11.5%) |
Adolescents (12 to 17 years) | 13 (39.4%) | NA | 13 (8.3%) |
Adults (18 to 64 years) | NA | 99 (80.5%) | 99 (63.5%) |
Elderly people; 65 to 74 years | NA | 22 (17.9%) | 22 (14.1%) |
Elderly people; 75 to 84 years | NA | 2 (1.6%) | 2 (1.3%) |
Body weight, kg | |||
Patients with data | 32 | 122 | 154 |
Mean (SD) | 32.7 (18.0) | 68.6 (14.6) | 61.1 (21.2) |
Median (Q1, Q3) | 27.5 (19.0, 44.0) | 69.0 (56.0, 78.0) | 64.0 (50.0, 75.0) |
Missing | 1 | 1 | 2 |
Primary diagnosis, n (%) | |||
Malignant haematopoietic | 19 (57.6%) | 119 (96.7%) | 138 (88.5%) |
Acute leukaemia of ambiguous lineage | 0 (0.0%) | 2 (1.6%) | 2 (1.3%) |
AML or related neoplasm | 6 (18.2%) | 43 (35.0%) | 49 (31.4%) |
ALL | 8 (24.2%) | 15 (12.2%) | 23 (14.7%) |
AMML | 0 (0.0%) | 1 (0.8%) | 1 (0.6%) |
NHL | 2 (6.1%) | 11 (8.9%) | 13 (8.3%) |
MDS/MPN | 3 (9.0%) | 47 (38.2%) | 50 (32.1%) |
Non-malignant (NOS) | 14 (42.4%) | 1 (0.8%) | 15 (9.6%) |
Missing | 0 (0.0%) | 3 (2.4%) | 3 (1.9%) |