Table 6 Association between plasma PUFAs levels and PASI scores or PASI response at 12 weeks in females
PUFAs (mol %) | PASI scores | PASI 75 | PASI 90 | PASI 100 | ||||
|---|---|---|---|---|---|---|---|---|
β (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
Omega-3 | ||||||||
 α-Linolenic acid (18:3n3) | − 0.20 (− 1.01, 0.61) | 0.627 | 1.76 (0.65, 4.78) | 0.268 | 1.63 (0.73, 3.60) | 0.231 | 1.04 (0.46, 2.34) | 0.933 |
 Eicosapentaenoic acid (20:5n3) | 0.58 (− 1.37, 2.53) | 0.560 | 0.16 (0.02, 1.41) | 0.099 | 0.19 (0.03, 1.50) | 0.116 | 0.47 (0.06, 3.90) | 0.488 |
 Docosahexaenoic acid (22:6n3) | 0.06 (− 0.45, 0.58) | 0.812 | 0.55 (0.31, 0.99) | 0.047 | 0.38 (0.17, 0.84) | 0.018 | 0.54 (0.25, 1.18) | 0.121 |
 Omega-3 PUFAs | 0.02 (− 0.42, 0.45) | 0.945 | 0.67 (0.41, 1.11) | 0.119 | 0.66 (0.43, 1.02) | 0.060 | 0.71 (0.43, 1.16) | 0.170 |
Omega-6 | ||||||||
 Linoleic acid (18:2n6-cis) | 0.00 (− 0.25, 0.26) | 0.991 | 1.04 (0.79, 1.38) | 0.781 | 1.02 (0.81, 1.28) | 0.854 | 0.96 (0.74, 1.23) | 0.742 |
 Eicosadienoic acid (20:2n6) | 5.60 (− 0.57, 11.76) | 0.076 | 0.01 (0.00, 11.86) | 0.195 | 0.00 (0.00, 2.54) | 0.093 | 0.06 (0.00, 47.05) | 0.407 |
 Dohomo-γ-Linolenic Acid (20:3n6) | 34.82 (7.24, 62.40) | 0.013 | 0.00 (0.00, 0.00) | 0.019 | 0.00 (0.00, 5.79) | 0.064 | 0.00 (0.00, 129217.71) | 0.207 |
 Arachidonic acid (20:4n6) | 0.17 (− 0.09, 0.43) | 0.196 | 0.74 (0.53, 1.03) | 0.072 | 0.79 (0.61, 1.03) | 0.084 | 0.94 (0.71, 1.23) | 0.644 |
 Omega-6 PUFAs | 0.11 (− 0.09, 0.31) | 0.288 | 0.84 (0.65, 1.09) | 0.183 | 0.89 (0.74, 1.07) | 0.219 | 0.94 (0.78, 1.14) | 0.539 |
 Omega-6/3 ratio | 0.10 (− 0.45, 0.65) | 0.723 | 1.16 (0.61, 2.19) | 0.657 | 1.39 (0.83, 2.33) | 0.205 | 1.29 (0.75, 2.23) | 0.361 |