Table 5 Association between plasma PUFAs levels and PASI scores or PASI response at 12 weeks in males
PUFAs (mol %) | PASI scores | PASI 75 | PASI 90 | PASI 100 | ||||
|---|---|---|---|---|---|---|---|---|
β (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
Omega-3 | ||||||||
 α-Linolenic acid (18:3n3) | − 0.18 (− 0.82, 0.46) | 0.580 | 1.03 (0.79, 1.35) | 0.840 | 0.98 (0.75, 1.30) | 0.910 | 0.90 (0.64, 1.27) | 0.545 |
 Eicosapentaenoic acid (20:5n3) | 0.14 (− 1.26, 1.54) | 0.840 | 1.10 (0.60, 2.01) | 0.767 | 1.55 (0.85, 2.84) | 0.157 | 1.20 (0.63, 2.28) | 0.586 |
 Docosahexaenoic acid (22:6n3) | 0.23 (− 0.35, 0.81) | 0.437 | 1.01 (0.79, 1.30) | 0.908 | 1.05 (0.83, 1.34) | 0.681 | 1.25 (0.95, 1.64) | 0.117 |
 Omega-3 PUFAs | 0.05 (− 0.34, 0.43) | 0.810 | 1.02 (0.87, 1.20) | 0.781 | 1.05 (0.90, 1.23) | 0.541 | 1.08 (0.90, 1.30) | 0.391 |
Omega-6 | ||||||||
 Linoleic acid (18:2n6-cis) | − 0.07 (− 0.35, 0.20) | 0.597 | 1.01 (0.90, 1.14) | 0.867 | 1.04 (0.92, 1.17) | 0.548 | 1.10 (0.95, 1.27) | 0.209 |
 Eicosadienoic acid (20:2n6) | − 1.10 (− 7.09, 4.88) | 0.718 | 6.94 (0.50, 97.12) | 0.150 | 2.04 (0.17, 24.93) | 0.578 | 1.70 (0.10, 30.50) | 0.717 |
 Dohomo-γ-linolenic acid (20:3n6) | 27.88 (− 11.57, 67.33) | 0.166 | 0.02 (0.00, 358272.69) | 0.645 | 0.00 (0.00, 64155.96) | 0.452 | 0.00 (0.00, 2955.26) | 0.202 |
 Arachidonic acid (20:4n6) | 0.10 (− 0.12, 0.33) | 0.365 | 0.99 (0.90, 1.08) | 0.815 | 1.03 (0.94, 1.14) | 0.504 | 1.10 (0.99, 1.23) | 0.089 |
 Omega-6 PUFAs | 0.04 (− 0.16, 0.24) | 0.676 | 1.00 (0.92, 1.08) | 0.963 | 1.05 (0.96, 1.14) | 0.287 | 1.14 (1.03, 1.27) | 0.014 |
 Omega-6/3 ratio | 0.12 (− 0.62, 0.38) | 0.634 | 0.99 (0.81, 1.22) | 0.932 | 1.07 (0.87, 1.32) | 0.523 | 0.99 (0.77, 1.26) | 0.908 |