Fig. 3

The Notch 5-TSPs signature performance in non-TNBC samples was compared with similar signatures. A The Notch 5-TSPs signature was evaluated in all non-TNBC, ER/PR + , and ER-/HER2 + samples. B Receiver operating characteristic (ROC) curves comparing the performance of the Notch 5-TSPs signature in predicting the response to NACT in TNBC with similar signatures in the two testing sets. Each table displays the Area under the ROC curve (AUC), 95% confidence interval (CI), and p-value from Delong’s test, testing the hypothesis that the AUC of the Notch 5-TSPs signature is greater than each respective signature’s AUC. TSPs top-scoring pairs. TNBC triple-negative breast cancer, AR androgen receptor, EMT epithelial-mesenchymal transition, MesenchStem mesenchymal stem-like, GF growth factor