Fig. 2

CircTENM3 inhibits PCa progression in vitro. A, B qPCR was used to determine the efficacy of circTENM3 overexpression in DU145 and PC3 cells, compared to the negative control (Ad-NC). N = 4. C, D, CCK-8 assays were performed in DU145 and PC3 cell with circTENM3 overexpression. N = 4. E, F, EdU assays were performed in DU145 and PC3 cell with circTENM3 overexpression. N = 4. Scale bar = 50 μm. G, H, Scratch assays were performed in DU145 and PC3 cell with circTENM3 overexpression. N = 4. Scale bar = 200 μm. I, J, Transwell assays were performed in DU145 and PC3 cell with circTENM3 overexpression. N = 4. Scale bar = 50 μm. All data were presented as the mean ± SD. A, B, E, F, G, H, I, J unpaired Student’s t-test. C, D, Two-way ANOVA with Bonferroni post hoc test. *P < 0.05