Fig. 2From: PTPRH promotes the progression of non-small cell lung cancer via glycolysis mediated by the PI3K/AKT/mTOR signaling pathwayCorrelation of PTPRH expression with 18F-fluorodeoxyglucose (18F-FDG) semiquantitative indicators, the expression of proliferation markers and the expression of glycolysis-related proteins. A, B Detection of PTPRH expression by immunohistochemistry (×400). C Correlation of PTPRH expression with 18F-FDG accumulation and the expression levels of Ki67. D In patients with high levels of PTPRH expression, immunohistochemical staining revealed high expression levels of GLUT1, HK2, PKM2, and LDHA (×400), whereas patients with low levels of PTPRH expression expressed low levels of GLUT1, HK2, PKM2 and LDHA (× 400). E The expression levels of PTPRH correlated positively with SUVmax, MTV, and TLG values and the expression of Ki67, GLUT1, HK2, PKM2, LDHA. 18F-FDG: 18F-fluorodeoxyglucose; GLUT1: glucose transporter type 1; HK2: hexokinase 2; PKM2: pyruvate kinase M2; LDHA: lactate dehydrogenase A; SUVmax: maximum standard uptake valueBack to article page