Table 3 The clinical impacts of integrin β1 in cancer patients
From: The characteristics and the multiple functions of integrin β1 in human cancers
Tumor type | Expression | Clinical impacts | Reference |
|---|---|---|---|
Pancreatic cancer | up | Periampullary carcinoma, poorer prognosis; ductal pancreatic carcinoma, unrelated | [95] |
Gastric cancer | up | Associated with a shorter survival time | [96] |
Lung cancer | up | Associated with worse overall survival | [97] |
Breast cancer | up | Linked to decreased 10-year overall survival and disease-free survival | [98] |
Prostate cancer | down | Associated with biochemical recurrence | [99] |
Renal cell cancer | down | Positively related to prognosis | [100] |
Colorectal cancer | up | Linked to poor prognosis; independently correlated with shortened overall survival and disease-free survival | [101] |