Fig. 1
From: Caprin-1 influences autophagy-induced tumor growth and immune modulation in pancreatic cancer
High level of Caprin-1 is associated with worse prognosis in PDAC. A Heatmap plotting the differential expressed genes between early stage and advanced stage in PDAC tissues. B Heatmap plotting differential expressed genes between short-term survival and long-term survival patients. C Venn diagram intersected gene signatures between advanced stage vs. early stage and short-term survival vs. long-term survival. D IPA analysis indicated significant profiles regulated by 76 different genes identified from two datasets. E GO analysis indicated top biological processes regulated by different genes. F IHC staining showed expression of Caprin-1 in human normal pancreas, early stage and advanced PDAC tissues. G The levels of Caprin-1 between adjacent and PDAC tissues were tested by qRT-PCR. H The serum levels of Caprin-1 between healthy volunteers and PDAC patients were examined by ELISA. I Kaplan–Meier curve showed the prognosis of PDAC patients between Caprin-1High and Caprin-1Low tissues from TCGA database. J The prognosis of PDAC patients between Caprin-1High and Caprin-1Low groups in our dataset