Fig. 4

Relationship between SIX1 and cancer stem cells. A The lollipop plot depicts the correlation between SIX1 and tumor stemness in pan-cancer. The x-axis represents different types of tumors, while the y-axis illustrates the correlation between SIX1 expression and RNA stemness scores. Positive values indicate a positive correlation, whereas negative values indicate a negative correlation. Colors represent the significance of differential cancer, the size of the circles represents the number of samples analyzed, the larger the circle, the greater the number of samples. Correlation scatter plots illustrating the relationship between SIX1 expression and ALDH1A1, SOX2, EPCAM, and ITGB1 in breast cancer (panels B to E). A value of 0 denotes a positive correlation, while a value of r < 0 indicates a negative correlation. P < 0.05 is considered to be a meaningful correlation