Fig. 7
From: Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance
Ferroptosis activators and iron overload reduce FTC-133 viability, but do not affect 8505C viable cells. a–d Cytofluorimetric analysis of viability evaluated with Annexin V/PI assay on FTC-133 treated with FAC, Erastin and RSL3 (a, b) and on 8505C treated with FAC, Erastin and RSL3 (c, d). Data are shown as standard box and whiskers and viability is expressed as percentage of gated cells, n = 4 independent replicates for each experimental condition. *p-value < 0.05; **p-value < 0.01; ***p-value < 0.001; ****p-value < 0.0001 versus control. CTRL control, FAC ferric ammonium citrate, RSL3 RAS-selective lethal 3