Fig. 5
From: Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance
Erastin leads to ROS overproduction in FTC-133 but not in 8505C. a–d Representative plots of ROS production in FTC-133 (a) and in 8505C (c), using DCF in flow cytometry, following 30 min and 180 min of FAC and Erastin treatment. Percent fluorescence quantification of DCF for FTC-133 (b) and for 8505C (d) is expressed in the two time-points. Data are shown as mean ± SEM of n = 4 independent experiments. **p-value < 0.01 and ****p-value < 0.0001. CTRL control, FAC ferric ammonium citrate, MFI mean fluorescence intensity, DCF 2′,7′-dichlorodihydrofluorescein acetate