Fig. 5

The m6A modification have been implicated in several other canonical pathways, such as C-MYC, Wnt/β-catenin, p53, and the EMT. The METTL3, YTHDF2, IGF2BP3, FTO, and other regulators of m6A modification have the ability to influence various pathways such as p53, C-YMC, Wntβ-catenin, and EMT. They engage in diverse mechanisms to participate in the regulation of tumor proliferation, migration, and invasion in colorectal cancer, lung cancer, pancreatic cancer, breast cancer, and other types of cancer. Consequently, these regulators exert substantial influence on the initiation and progression of tumors. Image created with BioRender (https://biorender.com/)