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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Lycium barbarum glycopeptide alleviates neuroinflammation in spinal cord injury via modulating docosahexaenoic acid to inhibiting MAPKs/NF-kB and pyroptosis pathways

Fig. 6

Model illustrating the role of LbGp in the treatment of SCI by inducing microglia to secrete DHA to inhibit the MAPK/NF-κB and pyroptosis pathways. Activation of microglia and release of inflammatory factors following SCI. LbGp stimulates microglia to produce DHA by regulating the key enzymes FADS1 and FADS2 in microglia, and thus, DHA can improve neuro inflammation by inhibiting the MAPK/NF-kB and pyroptosis pathways group.

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Journal of Translational Medicine

ISSN: 1479-5876

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