Table 2 Coefficients of each model from lasso regressions
From: Multipredictor risk models for predicting individual risk of Alzheimer’s disease
Model 1 | Model 2 | Model 3 | |
|---|---|---|---|
CN models | |||
Age | 0.0296 | 0.0162 | 0.0067 |
ADAS11 | 0.0644 | 0.0579 | 0.0192 |
RAVLT | −0.0022 | −0.0042 | −0.0153 |
LM-DR | −0.1032 | −0.0984 | −0.0742 |
FAQ | 0.1939 | 0.2296 | 0.2116 |
History of depression | 0.4837 | 0.5139 | 0.2621 |
History of diabetes | 0.4864 | 0.5346 | – |
Systolic blood pressure | 0.0088 | 0.0107 | – |
APOE ε4 status | – | 0.3461 | – |
Hippocampus volume | – | −0.2277 | −0.2717 |
CSF Aβ | – | – | −0.0052 |
CSF p-tau | – | – | 0.0140 |
MCI models | |||
Age | 0.0025 | – | |
ADAS11 | 0.0643 | 0.0674 | 0.0474 |
MMSE | −0.0243 | −0.0120 | −0.0019 |
RAVLT | −0.0324 | −0.0316 | −0.0292 |
LM-DR | −0.1060 | −0.0647 | −0.0602 |
FAQ | 0.0843 | 0.0746 | 0.0797 |
History of depression | 0.0013 | 0.0020 | 0.0680 |
APOE ε4 status | – | 0.4064 | – |
Hippocampus volume | – | −0.0653 | −0.1838 |
Whole brain volume | – | −0.0030 | −0.0020 |
CSF Aβ | – | – | −0.0044 |
CSF p-tau | – | – | 0.0074 |
Polygenic hazard score | – | – | 0.2257 |
ATN model | |||
MMSE | 0.0097 | – | – |
APOE ε4 status | 0.7533 | – | – |
Entorhinal volume | −0.6013 | – | – |
Ventricles volume | 0.0059 | – | – |
CSF Aβ | −0.0488 | – | – |
CSF tau | 0.0162 | – | – |