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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b

Fig. 2

LncRNA-Gm9866 regulates the expression of extracellular matrix genes in HSCs. A mRNA levels of α-SMA, COL-1, and MMP9 in lncRNA-Gm9866-overexpressing JS-1 cells by qPCR. B JS-1 cells were infected with lentivirus-control or lentivirus-mediated shRNA-Gm9866 for 72 h and further treated with 10 ng/mL TGFβ1 for an additional 24 h. Expression of lncRNA-Gm9866, α-SMA, COL-1, and MMP9 was detected by qPCR. */#P < 0.05, **/##P < 0.01. *P < 0.05 vs. shRNA-control, *P < 0.05 vs. LV-control in A and #P < 0.05 vs. shRNA-control + TGFβ1 in B

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