Fig. 2
From: LncRNA TDRKH-AS1 promotes breast cancer progression via the miR-134-5p/CREB1 axis
TDRKH-AS1 knockdown suppresses BC cell proliferation and invasion in vitro. A TDRKH-AS1 expression was reduced in MDA-MB-231 and MCF-1 cells using siRNAs. B, C The results of CCK-8 and colony formation assays demonstrated that the knockdown of TDRKH-AS1 inhibited the proliferation of breast cancer cells with a P value < 0.05. D, E Wound healing and transwell assays were conducted to assess the effect of si-TDRKH-AS1 on the invasion ability of breast cancer cells. The results showed a significant decrease in cell invasion ability in the knockdown group compared to the NC group. ∗P < 0.05 vs. NC group