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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson’s disease model via regulation of Nox4/ROS/Nrf2 signaling

Fig. 6

T-MSCs resist oxidative stress injury in PD mice through Keap1-Nrf2-SOD. a, b The content of GSSG and relative GSH/GSSG ratio after T-MSCs treatment of control or MPTP-induced PD mouse model (n = 3 per group). ch Western blotting analysis of Keap1, Nrf2, HO-1, SOD-1, and SOD-2 expression levels after T-MSCs treatment of control or MPTP-induced PD mouse model (n = 3 per group). The results are shown as mean ± SD. One-way ANOVA was used to analyze the data. *p < 0.05, **p < 0.01

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