Fig. 1

Neuroprotective effects of T-MSCs in MPTP-induced PD mice. a Experimental protocol schematic in vivo. b–d Representative images and quantification of IHC of TH-positive neurons in the striatum and SNpc of the control, T-MSCs, MPTP, and MPTP + T-MSCs groups (n = 3 per group). Scale bars, 1000 µm for images in striatum; 500, 200, and 100 µm for the series of images in SNpc. e, f Western blotting analysis showed the TH expression levels in the SN of the control, T-MSCs, MPTP, and MPTP + T-MSCs groups (n = 3 per group). The results are shown as mean ± SD. One-way ANOVA was used to analyze the data. *p < 0.05, **p < 0.01