Fig. 7

SIRT7 regulates oxidative stress in cervical squamous cell carcinoma via USP39 and FOXM1. A TEM was applied to observe and calculate the number of autophagosomes in CaSki cells in each group. B The mRFP-GFP-LC3 adenovirus infection assay was used to examine the autophagy levels of CaSki cells in each group. C JC-1 staining assays were used to detect the mitochondrial membrane potential (MMP) of CaSki cells after indicated transfection. When the MMP was high, JC-1 produced red fluorescence. When the MMP was low, JC-1 produced green fluorescence. D DCFH-DA staining assays were used to determine the ROS levels in CaSki cells in each group. All results are representative of at least 3-independent experiments. ***p < 0.001; ##p < 0.01, ###p < 0.001