Fig. 9

Highly expressed SPOCK1 is associated with low infiltrating CD8⁺ T cells. A Differences in the distribution of T cell rejection and dysfunction scores in high and low SPOCK1 groups. B The relationship between SPOCK1 and CD8⁺ T cell infiltration was assessed by the TIMER database using multiple immune infiltration methods. C Representative tissue immunofluorescence images for SPOCK1 and CD8. (SPOCK1_High, n = 3; SPOCK1_Low, n = 3). Scale bar = 50 μm. (***p < 0.001; **p < 0.01; *p < 0.05; ns. no significance.)