Fig. 10

Identification of potential drugs for the treatment of SPOCK1. A Therapeutic drugs showed significant IC50 differences in high- and low-SPOCK1 groups. B CMap-based screening of the potential drugs for SPOCK1. C Subcutaneous transplantation tumor isolates. (D) Tumor weight of mice after subcutaneous injection with PBS (n = 6) or VER-155008 (n = 6). E Tumor growth of subcutaneous LUAD tumors over time. Data are expressed as mean ± SD (***p < 0.001; **p < 0.01; *p < 0.05; ns. no significance.)