Fig. 5
From: Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis
Dysregulated palmitoylation is associated with immunotherapy response in human cancers. A The spearman correlation heatmap shows the correlations between the palmitoylation-related genes expressions and the 47 types of immune regulators in pan-cancer. B Correlations between palmitoyl-acyltransferases (Upper) or de-palmitoyl-acyltransferases (Lower) gene expression and TMB in pan-cancer. C Correlations between palmitoyl-acyltransferases (Upper) or de-palmitoyl-acyltransferases (Lower) gene expression and MSI in pan-cancer. D Kaplan–Meier curves and response to anti-PD-1 therapy in Low- and High- palmitoyl-acyltransferases (Left) or de-palmitoyl-acyltransferases (Right) gene expression subgroups of IMvigor210 Cohort (Anti-PD-L1, Urological Tumors)