Intestinal microbiota and metabolome perturbations in ischemic and idiopathic dilated cardiomyopathy

Table 2 Clinical characteristics of ICM and IDCM participants

Characteristics	ICM (n = 20)	IDCM (n = 22)	P
Age (year)	63	56	0.043
Sex (male)	16	17	0.83
Smoking	9	8	0.654
Alcohol intake	1	2	0.607
SBP (mmHg)	127	131	0.644
DBP (mmHg)	81	87	0.165
Diabetes mellitus	13	0	< 0.001
Hypertension	13	5	0.006
Atherosclerosis	4	0	0.27
LA (mm)	40.7	45.14	0.071
LVEDd (mm)	57.75	66.36	< 0.001
LVEDs (mm)	47.05	55.59	< 0.001
IVS (mm)	10.94	10.41	0.313
LVPW (mm)	10.5	10.41	0.84
RV (mm)	23.5	25.55	0.143
EF (%)	34.65	31.73	0.178
RWMA	8	0	0.001
LDH (U/L)	255.68	255.68	0.687
HBD (U/L)	154.64	152.08	0.871
BUN (mmol/L)	9.79	7.77	0.084
Cr (umol/L)	144.08	102.23	0.013
TC (mmol/L)	4.94	5.11	0.776
TG (mmol/L)	1.67	1.57	0.801
HDL (mmol/L)	1.02	1.14	0.227
LDL (mmol/L)	3.15	3.20	0.891
Gensini scores	81.6	0.5	< 0.001
NT-proBNP(pg/ml)	6089.88	4277.78	0.423
CK-MB (ng/ml)	3.0017	4.23	0.419
MYO (ng/ml)	78.91	67.21	0.634
TnT (ng/ml)	136.14	105.75	0.707
Medication use
ACEI/ARB	4	1
CCB	3	2
Biguanide hypoglycemic agents	7	0
Sulphonylurea	5	0
Statins	3	0

SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, LA left atrium, LVEDd left ventricular end-diastolic dimension, LVEDs left ventricular end-systolic dimension, IVS interventricular septum, LVPW left ventricular posterior wall, RV right ventricle, LVEF left ventricular ejection fraction, RWMA Regional wall motion abnormality, LDH lactate dehydrogenase, HBD hydroxyl butyric dehydrogenase, BUN blood urea nitrogen, Cr creatinine, TC total cholesterol, TG triglyceride, HDL high density lipoprotein, LDL low density lipoprotein, CK-MB creatine phosphokinase-isoenzyme-MB, MYO myoglobin, TNT troponin-T, ICM ischemic dilated cardiomyopathy, IDCM idiopathic dilated cardiomyopathy

ISSN: 1479-5876