Fig. 2
From: Intestinal microbiota and metabolome perturbations in ischemic and idiopathic dilated cardiomyopathy
Overall pattern of fecal metabolome in ICM and IDCM. A, B The scatter plots of OPLS-DA show an obvious metabolic separation of ICM and IDCM compared to HC, respectively. Volcano plots reveal the metabolite alterations in C ICM and D IDCM versus HC. Up and down represented significantly elevated and decreased fecal metabolites in the disease group compared to HC. E Box plots show specific and common metabolites in ICM and IDCM after adjustment for confounders. *P < 0.05, **P < 0.01, ***P < 0.001. F, G Metabolome view of dysregulated pathways observed in ICM and IDCM compared with HC, respectively. OPLS-DA orthogonal partial least squares-discriminant analysis