Fig. 5

Outcome of MTB-recommended treatment. (a) Kaplan–Meier analysis of TTP by OncoKB level (all 19 patients treated as per MTB recommendations). (b–e) Comparisons of MTB patients receiving further post-MTB treatment(s) vs patients receiving no further treatment (n = 8 vs 11, black vs blue). Variables selected for comparison: (b) time from first standard therapy line to MTB accrual, (c) number of pre-MTB therapy lines, (d) TTP of MTB-recommended therapy, and (e) Overall Survival (OS) from MTB accrual to last follow up. (f) linear regression of treatment duration (MTB-recommended vs post-MTB treatments) for each of the 8 patients receiving post-MTB treatment(s). Patient ID numbers are from Fig. 4. When significant, differences/correlations are noted in red.