Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis

Table 3 Example of one of the combinatorial disease signatures identified by the PrecisionLife combinatorial analysis of the Severe long COVID cohort

SNP id/genotype	Mapped genes	Severe cohort case count for individual SNPs (control count, odds ratio)	Severe cohort case count for disease signature (control count, odds ratio)
rs2025994/0	*SNX9*	396 (703, 1.06)
rs6777173/0	KLF15	164 (226, 1.36)	57 (23, 4.67)
rs11072524/1	RYR3	141 (186, 1.43)

Bold text indicates the critical (RF-scored) SNPs (and the genes to which they are mapped) in this signature

ISSN: 1479-5876