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Table 2 Summary of PrecisionLife combinatorial analysis results on Severe and Fatigue Dominant long COVID cohorts generated from the GOLD study

From: Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis

 

Severe cohort

Fatigue dominant cohort

Total disease signatures (n)

1188

1435

Disease signatures by number of component SNPs (n)

0, 2, 88, 322, 776

0, 25, 191, 225, 994

Odds ratio of disease signatures (relative to mean odds, Median [Q1-Q3])

77.9 [19.5—80.0]

22.5 [9.4—23.6]

RF scored “critical” SNPs (n)

86

84

RF scored genes (n)

43

36 (35 after ancestry confounder check)

Cases containing at least one disease signature (%)

100%

100%