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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway

Fig. 3

HIF1A bound to LINC02913 promoter region to inhibit its expression. A The transfection efficiency of HIF1A overexpression plasmid (HIF1A) and siRNA (si-HIF1A) was detected using western blot; B LINC02913 expression was detected after HIF1A overexpression and knockdown using qRT-PCR; C the binding of HIF1A with LINC02913 promoter region was verified using ChIP assay; D the binding between HIF1A and LINC02913 promoter region was verified using the dual-luciferase reporter gene assay; **p < 0.01, compared with the vector group; ##p < 0.01, compared with the si-NC group

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Journal of Translational Medicine

ISSN: 1479-5876

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