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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Spatiotemporal evolution of AML immune microenvironment remodeling and RNF149-driven drug resistance through single-cell multidimensional analysis

Fig. 1

Transcriptomic profiling of individual AML cells. A Cell clustering across varying resolutions. B t-SNE and UMAP visualizations of 84 acute myeloid leukemia samples compared to 9 healthy control samples. C t-SNE and UMAP representations of 11 primary cell types identified within AML. D Dot plots highlighting the characteristic genes with high expression across 101 cell clusters. Dot size corresponds to the percentage of cells expressing specific markers, while the color gradient reflects the average expression level of these markers

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