Table 1 Estimated effects of genetic variants in antidiabetic drugs targets on intracerebral hemorrhage
From: Genetically proxied antidiabetic drugs targets and stroke risk
Drug class | Proxy genes | OR | (95% CI) | P value |
|---|---|---|---|---|
Sulfonylureas | KCNJ11 + ABCC8 | 0.781 | 0.001−434.992 | 0.939 |
rs757110 | 0.700 | 2.02 × 10−4−2425.925 | 0.932 | |
Insulin/Insulin analogues | INSR | 1,122,841 | 0.031–4.01 × 1013 | 0.116 |
GLP-1 analogues | GLP1R | 0.029 | 3.39 × 10−9−248751.7 | 0.664 |
Thiazolidinediones | PPARG | 4.26 × 10−5 | 8.46 × 10−12−214.564 | 0.201 |