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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress–mitophagy

Fig. 5

The mRNA expression profiles in ccRCC cells after NR3C1 knockdown. A Volcano map of diferentially expressed genes (DEGs) between the control and sh-NR3C1 groups. Red represents up-regulated DEGs, blue represents down-regulated DEGs, and gray represents non-DEGs. B The heatmap diagram illustrates the expression levels of DEGs in each group, with a gradient from blue to red indicating down-regulation to up-regulation of the genes. C Transcription factor regulatory network of DEGs between two groups. GO (D) and KEGG (E) pathway analysis of DEGs. Red represents up-regulated enriched pathways, blue represents down-regulated enriched pathways. DEGs, differentially expressed genes; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes

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Journal of Translational Medicine

ISSN: 1479-5876

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