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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Genetic evidence strengthens the bidirectional connection between gut microbiota and periodontitis: insights from a two-sample Mendelian randomization study

Fig. 1

The core design and key assumptions of the present MR study. IVW inverse-variance weighted, the main analysis to investigate the association between exposure and outcome, LD linkage disequilibrium, it is used to calculate the correlations between SNPs; MR Mendelian randomization, SNP single nucleotide polymorphism, as genetic instrumental variables for the exposure and outcome, MR-PRESSO Mendelian randomization pleiotropy RESidual Sum and Outlier, a method for testing and correcting pleiotropic biases in SNPs

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