Fig. 1From: Genetic evidence strengthens the bidirectional connection between gut microbiota and periodontitis: insights from a two-sample Mendelian randomization studyThe core design and key assumptions of the present MR study. IVW inverse-variance weighted, the main analysis to investigate the association between exposure and outcome, LD linkage disequilibrium, it is used to calculate the correlations between SNPs; MR Mendelian randomization, SNP single nucleotide polymorphism, as genetic instrumental variables for the exposure and outcome, MR-PRESSO Mendelian randomization pleiotropy RESidual Sum and Outlier, a method for testing and correcting pleiotropic biases in SNPsBack to article page