Association of diabetes risk reduction diet with renal cancer risk in 101,755 participants: a prospective study

Table 2 Hazard ratios of the association of diabetes risk reduction diet score with the risk of renal cancer

Quartiles of DRRD score	Number of cases	Person-years	Incidence rate per 1000 person-years (95% confidence interval)	Hazard ratio (95% confidence interval)
Quartiles of DRRD score	Number of cases	Person-years		Unadjusted	Model 1^a	Model 2^b
Quartile 1 (9–23)	162	243,233.1	0.67 (0.57, 0.78)	1.00 (reference)	1.00 (reference)	1.00 (reference)
Quartile 2 (24–27)	133	256,240.4	0.52 (0.44, 0.62)	0.78 (0.62, 0.98)	0.81 (0.64, 1.02)	0.85 (0.68, 1.08)
Quartile 3 (28–30)	73	175,613.0	0.42 (0.33, 0.52)	0.62 (0.47, 0.82)	0.68 (0.52, 0.90)	0.75 (0.57, 1.00)
Quartile 4 (31–45)	78	224,251.0	0.35 (0.28, 0.43)	0.52 (0.40, 0.68)	0.61 (0.46, 0.80)	0.71 (0.54, 0.94)
P_trend				< 0.001	< 0.001	0.008

DRRD, diabetes risk reduction diet
^aModel 1: Adjusted for age (years), sex (male, female), race (white, non-white), marital status (married or living as married, no), educational level (college below, college graduate, postgraduate)
^bModel2: Adjusted for model 1 plus body mass index (kg/m2), smoking status (never, current, former), smoking pack-years (continuous), alcohol consumption (g/day), ibuprofen use (no, yes), arm (intervention, control), family history of renal cancer (no, yes), history of diabetes (no, yes), history of hypertension (no, yes) and energy intake from diet (kcal/day)

ISSN: 1479-5876