Table 2 Human TLRs and their major ligands
From: Mechanisms and research advances in mRNA antibody drug-mediated passive immunotherapy
TLRs | Ligands |
|---|---|
TLR1 | Triacylated lipopeptides |
TLR2 | Peptidoglycans, lipoproteins, lipopeptides, phospholipoman, lipoarabinomannan, porins |
TLR3 | dsRNA |
TLR4 | Lipopolysaccharide, envelope proteins, heat-shockproteins |
TLR5 | Flagellin |
TLR6 | Zymosan, diacylated lipopeptides |
TLR7 | ssRNA |
TLR8 | ssRNA |
TLR9 | CpG-DNA, hemozoin |
TLR10 | Unclear |