Clinical application of calcium silicate-based bioceramics in endodontics

Table 4 The major research findings of calcium silicate-based bioceramics in apexification

Application	Material	Main findings	References
Apexification	MTA	Mixing MTA with amalgam might improve root closure.	[106]
		Apexification with MTA possessed excellent sealing ability and could reduce severe periapical lesions.	[107,108,109,110]
		The application of absorbable materials and platelet-derived growth factors before the placement of MTA could elevate the success rate of apexification.	[115, 116]
		The extrusion of MTA might delay the healing of periapical lesion, but it was unnecessary to remove MTA by surgery, if the healing of periapical lesions could continue by itself.	[117,118,119,120]
		3 mm thickness of MTA followed by post-core and crown repair could achieve better fracture resistance.	[121, 122]
	Biodentine	Biodentine displayed better aesthetical outcome and induced more deposition of hydroxyapatite crystals on the interface between the material and the dentin.	[125, 126]
		3 mm thickness of Biodentine or 4 mm thickness of ProRootMTA could achieve the lowest bacterial leakage and the best marginal adaptation in apexification.	[128]

ISSN: 1479-5876