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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Cytosine–phosphate–guanine oligodeoxynucleotides alleviate radiation-induced kidney injury in cervical cancer by inhibiting DNA damage and oxidative stress through blockade of PARP1/XRCC1 axis

Fig. 7

Schematic diagram of the molecular mechanism by which CpG-ODNs regulate PARP1/XRCC1 axis to affect DNA damage and oxidative stress response in RKI in cervical cancer. CpG-ODNs may attenuate RKI in cervical cancer by blocking PARP1/XRCC1 axis activation and inhibiting DNA damage and oxidative stress in renal tubular epithelial cells

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