Fig. 3From: Synovium is a sensitive tissue for mapping the negative effects of systemic iron overload in osteoarthritis: identification and validation of two potential targetsIdentification of JUN and ZFP36 as potential target genes in the development of OA-associated synovitis. A Protein–protein interaction network of the hub genes. Red represents upregulation and blue represents downregulation. B Venn diagram for screening JUN and ZFP36. C Distribution of JUN and ZFP36 expression in the internal datasets. D Diagnostic ROC curves of JUN and ZFP36 for OA-associated synovitis. E GSEA analysis of JUN and ZFP36. DEGs, differentially expressed genes; ROC, receiver operating characteristic; GSEA, gene set enrichment analysis; **P < 0.01, ***P < 0.001 versus the control groupBack to article page