From: Potent antitumor efficacy of human dental pulp stem cells armed with YSCH-01 oncolytic adenovirus
Experiments | Virus initial infectious dose (VP/cell) | Intracellular viral payload(ifu/cell) | The % index (ifu/VP) | Intracellular VP per cell | Injected cells (YSCH-01/hDPSCs) number in vivo | The amounts of virus delivered by hDPSCs in vivo |
---|---|---|---|---|---|---|
EXP 1 | 1000 | 5.13 × 10–3 | 0.884 | 0.58 | 2 × 106 | 1.16 × 106 |
EXP 2 | 1000 | 8.43 × 10–3 | 0.878 | 0.96 | 2 × 106 | 1.96 × 106 |
Average | 1000 | 6.78 × 10–3 | / | 0.77 | 2 × 106 | 1.54 × 106 |