Fig.1

Identification of the MYCN-related lncRNA AC142119.1. A Heatmap depicts the differentially expressed lncRNAs between MYCN-amplified cell line SK-N-DZ and MYCN-non-amplified cell line SH-SY5Y. B Three lncRNAs candidates located nearby the MYCN locus. C The genomic location of AC142119.1 annotated by UCSC database. D PCR products of 5′ and 3′ RACE analyses subjected to agarose gel electrophoresis. E Cytoplasmic and nuclear fractionation of SK-N-DZ cells followed by qRT-PCR to determine the subcellular localization of AC142119.1 RNA. GAPDH and U6 were used as cytoplasmic and nuclear marker, respectively. F FISH detection of AC142119.1 transcript in SK-N-DZ cells. Scale bar, 50 μm